TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair

Hariharasudhan, G; Jeong, SY; Kim, MJ; Jung, SM; Seo, G; Moon, JR; Lee, SM; Chang, IY; Kee, Y; You, HJ; Lee, JH

You, HJ; Lee, JH (通讯作者)，Chosun Univ, Sch Med, Lab Genom Instabil & Canc Therapeut, 309 Pilmun Daero, Gwangju 61452, South Korea.;Lee, JH (通讯作者)，Chosun Univ, Sch Med, Dept Cellular & Mol Med, 309 Pilmun Daero, Gwangju 61452, South Korea.;You, HJ (通讯作者)，Chosun Univ, Sch Med, Dept Pharmacol, 309 Pilmun Daero, Gwangju 61452, South Korea.;Kee, Y (通讯作者)，Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept New Biol, 333 Techno Joongang Daero, Daegu 42988, South Korea.

NUCLEIC ACIDS RESEARCH, 2022; 50 (3): 1501

Abstract

Homologous recombination (HR) is critical for error-free repair of DNA double-strand breaks. Chromatin loading of RAD51, a key protein that mediates t......

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