Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond

Zhao, B; Tsai, YC; Jin, B; Wang, BF; Wang, YY; Zhou, H; Carpenter, T; Weissman, AM; Yin, J

Zhao, B (corresponding author), Shanghai Jiao Tong Univ, Shanghai 200240, Peoples R China.; Weissman, AM (corresponding author), NCI, Frederick, MD 21702 USA.; Yin, J (corresponding author), Georgia State Univ, Atlanta, GA 30302 USA.

PHARMACOLOGICAL REVIEWS, 2020; 72 (2): 380

Abstract

Ubiquitin (UB) transfer cascades con-sisting of E1, E2, and E3 enzymes constitute a complex network that regulates a myriad of biologic processes by m......

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