Identification of the functional PD-L1 interface region responsible for PD-1 binding and initiation of PD-1 signaling

Carter, R; Alanazi, F; Sharp, A; Roman, J; Luchini, A; Liotta, L; Paige, M; Brown, AM; Haymond, A

Carter, R (通讯作者),George Mason Univ, Ctr Appl Prote & Mol Med, Fairfax, VA 22030 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2023; 299 (12):

Abstract

The PD-1/PD-L1 checkpoint pathway is important for regulating immune responses and can be targeted by immunomodulatory drugs to treat a variety of imm......

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