Population Pharmacokinetics of Apalutamide and its Active Metabolite N-Desmethyl-Apalutamide in Healthy and Castration-Resistant Prostate Cancer Subjects

Perez-Ruixo, C; Perez-Blanco, JS; Chien, C; Yu, MG; Ouellet, D; Perez-Ruixo, JJ; Ackaert, O

Ackaert, O (corresponding author), Janssen Res & Dev, Antwerp, Belgium.

CLINICAL PHARMACOKINETICS, 2020; 59 (2): 229

Abstract

Background Apalutamide is a next-generation androgen receptor inhibitor approved for treatment of subjects with high-risk, non-metastatic, castration-......

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