IL21 Therapy Combined with PD-1 and Tim-3 Blockade Provides Enhanced NK Cell Antitumor Activity against MHC Class I-Deficient Tumors

Seo, H; Kim, BS; Bae, EA; Min, BS; Han, YD; Shin, SJ; Kang, CY

Kang, CY (reprint author), Seoul Natl Univ, Bldg 29,Rm 117,Gwan Ak Ro 1, Seoul 08826, South Korea.

CANCER IMMUNOLOGY RESEARCH, 2018; 6 (6): 685

Abstract

Increased expression of coinhibitory molecules such as PD-1 and Tim-3 on NK cells has been demonstrated in advanced cancer patients who harbor MHC cla......

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