Na+/H+ exchanger isoform 1 activity in AQP2-expressing cells can be either proliferative or anti-proliferative depending on extracellular pH

Mazzocchi, M; Di Giusto, G; Porta, M; Pizzoni, A; Beltramone, N; Ford, P; Capurro, C; Rivarola, V

Rivarola, V (corresponding author), Univ Buenos Aires, CONICET, Inst Fisiol & Biofis Bernardo Houssay IFIBIO HOUS, Buenos Aires, DF, Argentina.; Rivarola, V (corresponding author), Univ Buenos Aires, CONICET, Inst Fisiol & Biofis Bernardo Houssay IFIBIO HOUS, Lab Biomembranas, Paraguay 2155 Piso 7,C1121ABG, Buenos Aires, DF, Argentina.

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2020; 76 (1): 37

Abstract

We have previously shown in renal cells that expression of the water channel Aquaporin-2 increases cell proliferation by a regulatory volume mechanism......

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