DNA methylation occurring in Cre-expressing cells inhibits loxP recombination and silences loxP-sandwiched genes

Liu, RC; Long, Q; Zou, XP; Wang, Y; Pei, Y

Pei, Y (corresponding author), Southwest Univ, Chongqing Key Lab Applicat & Safety Control Genet, Biotechnol Res Ctr, 2 Tiansheng Rd Beibei, Chongqing 400715, Peoples R China.

NEW PHYTOLOGIST, 2021; 231 (1): 210

Abstract

The low DNA recombination efficiency of site-specific recombinase systems in plants limits their application; however, the underlying mechanism is unk......

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