CCNB1IP1 prevents ubiquitination-mediated destabilization of MYCN and potentiates tumourigenesis of MYCN-amplificated neuroblastoma

Zhou, Y; Yan, H; Zhou, Q; Wang, PG; Yang, F; Yuan, ZQ; Du, QM; Zhai, B

Du, QM (通讯作者)，Nanjing Med Univ, Nanjing Hosp 1, Gen Clin Res Ctr, Nanjing 210006, Peoples R China.;Zhai, B (通讯作者)，Zhengzhou Univ, Henan Childrens Hosp, Zhengzhou Childrens Hosp, Henan Prov Clin Res Ctr Pediat Dis,Childrens Hosp,, Zhengzhou 450018, Peoples R China.

CLINICAL AND TRANSLATIONAL MEDICINE, 2023; 13 (7):

Abstract

BackgroundMYCN amplification as a common genetic alteration that correlates with a poor prognosis for neuroblastoma (NB) patients. However, given the ......

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