Impact of Genetic Variants of ATP Binding Cassette B1, AICAR Transformylase/IMP Cyclohydrolase, Folyl-polyglutamate Synthetase, and Methylenetetrahydrofolate Reductase on Methotrexate Toxicity

Sala-Icardo, L; Lamana, A; Ortiz, AM; Lorenzo, EG; Fresneda, PM; Garcia-Vicuna, R; Gonzalez-Alvaro, I

Gonzalez-Alvaro, I (reprint author), Hosp Univ La Princesa, Serv Reumatol, Madrid, Spain.

REUMATOLOGIA CLINICA, 2017; 13 (6): 318

Abstract

Objective: To analyze the effect of single nucleotide polymorphisms (SNPs) with well-known functional impact of methylenetetrahydrofolate reductase (M......

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