The discovery and optimization of a series of 2-aminobenzoxazole derivatives as ChemR23 inhibitors

Imaizumi, T; Kobayashi, A; Otsubo, S; Komai, M; Magara, M; Otsubo, N

Imaizumi, T (reprint author), Kyowa Kirin Co Ltd, R&D Div, Small Mol Drug Res Labs, 1188 Shimotogari, Nagaizumi, Shizuoka 4118731, Japan.

BIOORGANIC & MEDICINAL CHEMISTRY, 2019; 27 (21):

Abstract

A structural class of 2-aminobenzoxazole derivatives possessing biphenyltetrazole was discovered to be potent human ChemR23 inhibitors. We initially t......

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