Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction

Vanarotti, M; Grace, CR; Miller, DJ; Actis, ML; Inoue, A; Evison, BJ; Vaithiyalingam, S; Singh, AP; McDonald, ET; Fujii, N

Vanarotti, M; Fujii, N (reprint author), St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, 332 N Lauderdale St, Memphis, TN 38105 USA.

JOURNAL OF MOLECULAR BIOLOGY, 2018; 430 (17): 2857

Abstract

REV1 is a DNA damage tolerance protein and encodes two ubiquitin-binding motifs (UBM1 and UBM2) that are essential for REV1 functions in cell survival......

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