Helichrysetin inhibits gastric cancer growth by targeting c-Myc/PDHK1 axis-mediated energy metabolism reprogramming

Wang, P; Jin, JM; Liang, XH; Yu, MZ; Yang, C; Huang, F; Wu, H; Zhang, BB; Fei, XY; Wang, ZT; Xu, R; Shi, HL; Wu, XJ

Shi, HL; Wu, XJ (通讯作者)，Shanghai Univ Tradit Chinese Med, Res Ctr Shanghai Tradit Chinese Med Standardizat, Inst Chinese Mat Med,SATCM Key Lab New Resources, Shanghai Key Lab Compound Chinese Med,Key Lab Sta, Shanghai 201203, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2022; 43 (6): 1581

Abstract

Helichrysetin (HEL), a chalcone isolated from Alpinia katsumadai Hayata, has an antitumor activity in human lung and cervical cancers. However, the in......

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