AZD8186 in Combination With Paclitaxel in Patients With Advanced Gastric Cancer: Results From a Phase Ib/II Study (KCSG ST18-20)

Suh, KJ; Ryu, MH; Zang, DY; Bae, WK; Lee, HS; Oh, HJ; Kang, M; Kim, JW; Kim, BJ; Mortimer, PGS; Kim, HJ; Lee, KW

Lee, KW (通讯作者)，Seoul Natl Univ, Coll Med, Dept Internal Med, Bundang Hosp, 82, Gumi Ro 173 Beon Gil, Seongnam 13620, Gyeonggi Do, South Korea.

ONCOLOGIST, 2023; 28 (9): E823

Abstract

Background Loss of PTEN function leads to increased PI3K beta signaling. AZD8186, a selective PI3K beta/delta inhibitor, has shown anti-tumor activity......

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