Mismatch Repair (MMR) Gene Alteration and BRAF V600E Mutation Are Potential Predictive Biomarkers of Immune Checkpoint Inhibitors in MMR-Deficient Colorectal Cancer

Sahin, IH; Goyal, S; Pumpalova, Y; Sonbol, MB; Das, S; Haraldsdottir, S; Ahn, D; Ciombor, KK; Chen, Z; Draper, A; Berlin, J; Bekaii-Saab, T; Lesinski, GB; El-Rayes, BF; Wu, C

Sahin, IH (corresponding author), Emory Univ, Sch Med, Winship Canc Inst, 1365 Clifton Rd,NE 2080, Atlanta, GA 30322 USA.

ONCOLOGIST, ; ():

Abstract

Background Immune checkpoint inhibitor (ICI) therapy is highly effective in metastatic mismatch repair-deficient (MMR-D) colorectal cancer (CRC). In t......

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