Synthetic Route Design of AZD4635, an A(2A)R Antagonist

Littleson, MM; Campbell, AD; Clarke, A; Dow, M; Ensor, G; Evans, MC; Herring, A; Jackson, BA; Jackson, LV; Karlsson, S; Klauber, DJ; Legg, DH; Leslie, KW; Moravcik, S; Parsons, CD; Ronson, TO; Meadows, RE

Littleson, MM (reprint author), AstraZeneca, Chem Dev Pharmaceut Technol & Dev, Macclesfield Campus, Macclesfield SK10 2NA, Cheshire, England.

ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2019; 23 (7): 1407

Abstract

The AstraZeneca approach to synthetic Route Design is exemplified through our AZD4635 chemical development program. The identification of possible new......

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