Constitutively active ABL family kinases, TEL/ABL and TEL/ARG, harbor distinct leukemogenic activities in vivo

Yokota, A; Hirai, H; Shoji, T; Maekawa, T; Okuda, K

Okuda, K (reprint author), Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Mol Diagnost & Therapeut, Kamigyo Ku, 465 Kajii Cho, Kyoto 6028566, Japan.; Hirai, H (reprint author), Kyoto Univ Hosp, Dept Transfus Med & Cell Therapy, Sakyo Ku, 54 Kawahara C

LEUKEMIA, 2017; 31 (12): 2742

Abstract

ABL (ABL1) and ARG (ABL2) are highly homologous to each other in overall domain structure and amino-acid sequence, with the exception of their C termi......

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