ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the MYT1-Egln3-Sirt1 Axis

Hu, GW; Xia, YG; Chen, B; Zhang, JT; Gong, LZ; Chen, Y; Li, Q; Wang, Y; Deng, ZF

Deng, ZF (corresponding author), Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6, Dept Neurosurg, 600 Yishan Rd, Shanghai 200233, Peoples R China.; Li, Q; Wang, Y (corresponding author), Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6, Inst Microsurg Extrem, 600 Yishan Rd, Shanghai 200233, Peoples R China.

MOLECULAR THERAPY, 2021; 29 (1): 103

Abstract

Tissue stem cell senescence leads to stem cell exhaustion, which results in tissue homeostasis imbalance and a decline in regeneration capacity. Howev......

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