Therapeutic Drug Monitoring of Rivastigmine and Donepezil Under Consideration of CYP2D6 Genotype-Dependent Metabolism of Donepezil

Ortner, M; Stange, M; Schneider, H; Schroder, C; Buerger, K; Muller, C; Muller-Sarnowski, F; Diehl-Schmid, J; Forstl, H; Grimmer, T; Steimer, W

Ortner, M (corresponding author), Tech Univ Munich, Sch Med, Dept Psychiat & Psychotherapy, Klinikum Rechts Isar, Munich, Germany.

DRUG DESIGN DEVELOPMENT AND THERAPY, 2020; 14 (): 3251

Abstract

Background: The efficacy of acetylcholinesterase inhibitors (AChE-I) might depend on blood concentration. While rivastigmine metabolism is independent......

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