Immunoglobulin-like domain 4-mediated ligand-independent dimerization triggers VEGFR-2 activation in HUVECs and VEGFR2-positive breast cancer cells

Zhang, S; Gao, XP; Fu, W; Li, SW; Yue, LM

Yue, LM (reprint author), Sichuan Univ, Dept Physiol, West China Sch Preclin & Forens Med, 17,Sect 3 Renmin South Rd, Chengdu 610064, Sichuan, Peoples R China.

BREAST CANCER RESEARCH AND TREATMENT, 2017; 163 (3): 423

Abstract

The extracellular region (EC) of the vascular endothelial growth factor (VEGF) receptor-2 (VEGFR-2) contains seven immunoglobulin-like (Ig-like) domai......

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