Doxycycline Attenuates Leptospira-Induced IL-1 beta by Suppressing NLRP3 Inflammasome Priming

Zhang, WL; Xie, XF; Wu, DJ; Jin, XM; Liu, RX; Hu, XY; Fu, YH; Ding, Z; Zhang, NS; Cao, YG

Cao, YG (reprint author), Jilin Univ, Coll Vet Med, Key Lab Zoonosis Res, Minist Educ, Changchun, Jilin, Peoples R China.; Cao, YG (reprint author), Jilin Univ, Dept Clin Vet Med, Coll Vet Med, Changchun, Jilin, Peoples R China.

FRONTIERS IN IMMUNOLOGY, 2017; 8 ( ):

Abstract

Doxycycline (Dox), a semisynthetic antibiotic, has been reported to exert multiple immunomodulatory effects. Treatment with Dox has a satisfactory cur......

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