Small molecule DNA-PK inhibitors as potential cancer therapy: a patent review (2010-present)

Hu, SW; Hui, Z; Lirussi, F; Garrido, C; Ye, XY; Xie, T

Ye, XY; Xie, T (corresponding author), Hangzhou Normal Univ, Coll Pharm, Sch Med, Dept Med Chem, Hangzhou, Zhejiang, Peoples R China.; Garrido, C (corresponding author), Univ Bourgogne Franche Comte, INSERM Unit U1231, Label LIPSTIC, I SITE, 7 Bvd Jeanne dArc, F-21000 Dijon, France.

EXPERT OPINION ON THERAPEUTIC PATENTS, 2021; 31 (5): 435

Abstract

Introduction: DNA-dependent protein kinase (DNA-PK) plays a crucial role in the repair of DSBs via non-homologous end joining (NHEJ). Several DNA-PK i......

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