Uncovering the dosage-dependent roles of Arid1a in gastric tumorigenesis for combinatorial drug therapy

Loe, AKH; Francis, R; Seo, J; Du, LT; Wang, YS; Kim, JE; Hakim, SW; Kim, JE; He, HH; Guo, HY; Kim, TH

Kim, TH (corresponding author), Hosp Sick Children, Program Dev & Stem Cell Biol, Toronto, ON, Canada.; Kim, TH (corresponding author), Univ Toronto, Dept Mol Genet, Toronto, ON, Canada.; Guo, HY (corresponding author), Shandong Univ, Hosp 2, Dept Clin Lab, Jinan, Shandong, Peoples R China.; Guo, HY (corresponding author), Tumor Marker Detect Engn Lab Shandong Prov, Jinan, Shandong, Peoples R China.; Guo, HY (corresponding author), Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Cana

JOURNAL OF EXPERIMENTAL MEDICINE, 2021; 218 (6):

Abstract

Gastric cancer (GC) is one of the most common deadly cancers in the world. Although patient genomic data have identified AT-rich interaction domain 1A......

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