CDK9 inhibitors reactivate p53 by downregulating iASPP

Wu, JL; Liang, Y; Tan, Y; Tang, YG; Song, HX; Wang, ZY; Li, YT; Lu, M

Lu, M (corresponding author), Shanghai Jiao Tong Univ, Rui Jin Hosp, Sch Med, Shanghai Inst Haematol,State Key Lab Med Genom, Shanghai 200025, Peoples R China.

CELLULAR SIGNALLING, 2020; 67 ():

Abstract

Loss of p53's tumor-suppressive function, either via TP53 mutation or hyperactive p53 inhibitory proteins, is one of the most frequent events in the d......

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