Glucagon receptor antagonist upregulates circulating GLP-1 level by promoting intestinal L-cell proliferation and GLP-1 production in type 2 diabetes

Lang, S; Yang, J; Yang, K; Gu, LB; Cui, XN; Wei, TJ; Liu, JL; Le, YY; Wang, HN; Wei, R; Hong, TP

Wei, R; Hong, TP (corresponding author), Peking Univ, Hosp 3, Dept Endocrinol & Metab, Beijing, Peoples R China.; Wei, R; Hong, TP (corresponding author), Peking Univ, Hosp 3, Clin Stem Cell Res Ctr, Beijing, Peoples R China.

BMJ OPEN DIABETES RESEARCH & CARE, 2020; 8 (1):

Abstract

ObjectiveGlucagon receptor (GCGR) blockage improves glycemic control and increases circulating glucagon-like peptide-1 (GLP-1) level in diabetic anima......

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