PLPP/CIN-mediated Mdm2 dephosphorylation increases seizure susceptibility via abrogating PSD95 ubiquitination

Kim, JE; Lee, DS; Kim, TH; Park, H; Kim, MJ; Kang, TC

Kang, TC (corresponding author), Hallym Univ, Coll Med, Dept Anat & Neurobiol, Chunchon 24252, Kangwon Do, South Korea.

EXPERIMENTAL NEUROLOGY, 2020; 331 ():

Abstract

In the brain, murine double minute-2 (Mdm2), an E3-ubiquitin ligase, modulates neuronal excitability by regulating glutamate receptor and postsynaptic......

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