An optimized fixation method containing glyoxal and paraformaldehyde for imaging nuclear bodies

Yao, RW; Luan, PF; Chen, LL

Chen, LL (corresponding author), Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol,State Key Lab M, CAS Ctr Excellence Mol Cell Sci,Shanghai Key Lab, Shanghai 200031, Peoples R China.; Chen, LL (corresponding author), ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China.; Chen, LL (corresponding author), Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Sch Life Sci, Hangzhou 330106, Peoples R China.

RNA, 2021; 27 (6): 725

Abstract

The mammalian cell nucleus contains different types of membrane-less nuclear bodies (NBs) consisting of proteins and RNAs. Microscopic imaging has bee......

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