Stepwise crosstalk between aberrant Nf1, Tp53 and Rb signalling pathways induces gliomagenesis in zebrafish

Luo, JJ; Liu, P; Lu, CJ; Bian, WP; Su, DS; Zhu, CC; Xie, SL; Pan, YH; Li, NN; Cui, W; Pei, DS; Yang, XJ

Yang, XJ (corresponding author), Shantou Univ, Neurosci Ctr, Med Coll, Shantou 515041, Peoples R China.; Pei, DS (corresponding author), Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China.

BRAIN, 2021; 144 (): 615

Abstract

The molecular pathogenesis of glioblastoma indicates that RTK/Ras/PI3K, RB and TP53 pathways are critical for human glioma-genesis. Here, several tran......

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