Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor

Passos, V; Zillinger, T; Casartelli, N; Wachs, AS; Xu, ST; Malassa, A; Steppich, K; Schilling, H; Franz, S; Todt, D; Steinmann, E; Sutter, K; Dittmer, U; Bohne, J; Schwartz, O; Barchet, W; Goffinet, C

Goffinet, C (reprint author), TWINCORE Ctr Expt & Clin Infect Res, Inst Expt Virol, Hannover, Germany.; Goffinet, C (reprint author), Charite Univ Med Berlin, Inst Virol, Campus Charite Mitte, Berlin, Germany.; Goffinet, C (reprint author), Berlin Inst Hl

JOURNAL OF VIROLOGY, 2019; 93 (24):

Abstract

When expressed in virus-producing cells, the cellular multipass transmembrane protein SERINC5 reduces the infectivity of HIV-1 particles and is counte......

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