HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation

Ma, WJ; Cai, Y; Shen, YT; Chen, X; Zhang, LL; Ji, YA; Chen, ZH; Zhu, JW; Yang, XM; Sun, HL

Yang, XM; Sun, HL (corresponding author), Nantong Univ, Coinnovat Ctr Neuroregenerat, Jiangsu Clin Med Ctr Tissue Engn & Nerve Injury R, Key Lab Neuroregenerat Jiangsu, Nantong, Peoples R China.; Yang, XM; Sun, HL (corresponding author), Nantong Univ, Coinnovat Ctr Neuroregenerat, Jiangsu Clin Med Ctr Tissue Engn & Nerve Injury R, Minist Educ,NMPA Key Lab Res & Evaluat Tissue Eng, Nantong, Peoples R China.; Zhu, JW (corresponding author), Nantong Univ, Affiliated Hosp, Dept Orthoped, Nantong, Pe

FRONTIERS IN CELLULAR NEUROSCIENCE, 2021; 15 ():

Abstract

Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective t......

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