Modulation of the activated protein C pathway in severe haemophilia A patients: The effects of thrombomodulin and afactor V-stabilizing fab

Brophy, DF; Martin, EJ; Mohammed, BM; Barrett, JC; Kuhn, JG; Nolte, ME; Wiinberg, B; Holmberg, HL; Lund, J; Salbo, R; Waters, EK

Brophy, DF (reprint author), Virginia Commonwealth Univ, Richmond, VA 23284 USA.

HAEMOPHILIA, 2017; 23 (6): 941

Abstract

IntroductionThe thrombomodulin (TM)/activated protein C (APC) system is a key regulator of haemostasis, limiting amplification and propagation of the ......

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