Phase 1 study combining alisertib with nab-paclitaxel in patients with advanced solid malignancies

Lim, KH; Opyrchal, M; Acharya, A; Boice, N; Wu, NY; Gao, F; Webster, J; Lockhart, AC; Waqar, SN; Govindan, R; Morgensztern, D; Picus, J; Tan, BR; Baggstrom, MQ; Maher, CA; Wang-Gillam, A

Wang-Gillam, A (corresponding author), Washington Univ, Div Oncol, Barnes Jewish Hosp, St Louis, MO 63110 USA.; Wang-Gillam, A (corresponding author), Washington Univ, Alvin J Siteman Comprehens Canc Ctr, St Louis, MO 63110 USA.

EUROPEAN JOURNAL OF CANCER, 2021; 154 (): 102

Abstract

Aim: Aurora kinase A (AURKA) is a pleiotropic serine/threonine kinase that orchestrates mitotic progression. Paclitaxel stabilises microtubules and di......

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