Impaired Sphingosine-1-Phosphate Synthesis Induces Preeclampsia by Deactivating Trophoblastic YAP (Yes-Associated Protein) Through S1PR2 (Sphingosine-1-Phosphate Receptor-2)-Induced Actin Polymerizations

Liao, JJ; Zheng, YX; Hu, MY; Xu, P; Lin, L; Liu, XY; Wu, Y; Huang, B; Ye, X; Li, SS; Duan, R; Fu, HJ; Huang, JY; Wen, L; Fu, Y; Kilby, MD; Kenny, LC; Baker, PN; Qi, HB; Tong, C

Qi, HB; Tong, C (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, State Key Lab Maternal & Fetal Med Chongqing Muni, 1 Youyi Rd, Chongqing 400016, Peoples R China.

HYPERTENSION, 2022; 79 (2): 399

Abstract

Incomplete spiral artery remodeling, caused by impaired extravillous trophoblast invasion, is a fundamental pathogenic process associated with malplac......

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