Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis

Guo, JW; Song, ZH; Yu, J; Li, CY; Jin, CC; Duan, W; Liu, X; Liu, YY; Huang, S; Tuo, Y; Pei, F; Jian, ZY; Zhou, PY; Zheng, SY; Zou, ZW; Zhang, F; Gong, Q; Liang, SJ

Guo, JW (通讯作者)，Yangtze Univ, Sch Med, Dept Pharmacol, Jingzhou, Peoples R China.;Gong, Q (通讯作者)，Yangtze Univ, Sch Med, Dept Immunol, Jingzhou, Peoples R China.;Liang, SJ (通讯作者)，Sun Yat Sen Univ, Zhongshan Sch Med, Dept Pharmacol, Guangzhou, Peoples R China.

CELL DEATH & DISEASE, 2022; 13 (12):

Abstract

Ischemia/reperfusion (I/R)-induced liver injury with severe cell death is a major complication of liver transplantation. Transmembrane member 16A (TME......

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