The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis

Sun, JC; Roy, S

Roy, S (reprint author), Univ Wisconsin, Dept Pathol & Lab Med, 1111 Highland Ave, Madison, WI 53705 USA.; Roy, S (reprint author), Univ Wisconsin, Dept Neurosci, 1111 Highland Ave, Madison, WI 53705 USA.

DEVELOPMENTAL NEUROBIOLOGY, 2018; 78 (3): 340

Abstract

Alzheimer's disease (AD) is characterized by the accumulation of insoluble deposits of Amyloid (A) in brains. A is derived by sequential cleavage of t......

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