Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice

Liu, XY; Guo, GL; Kong, B; Hilburn, DB; Hubchak, SC; Park, S; LeCuyer, B; Hsieh, A; Wang, L; Fang, DY; Green, RM

Green, RM (reprint author), Northwestern Univ, Dept Med, Div Gastroenterol & Hepatol, Tarry 15-719,303 East Chicago Ave, Chicago, IL 60611 USA.

HEPATOLOGY, 2018; 68 (1): 304

Abstract

Bile acids are endogenous ligands of the nuclear receptor, farnesoid X receptor (FXR), and pharmacological FXR modulators are under development for th......

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