Design of acid-activated cell-penetrating peptides with nuclear localization capacity for anticancer drug delivery

Huang, SJ; Zhu, ZW; Jia, B; Zhang, W; Song, JJ

Zhang, W; Song, JJ (corresponding author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.

JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (10):

Abstract

Camptothecin (CPT), a DNA-toxin drug, exerts anticancer activity by inhibiting topoisomerase I. Targeted delivery of CPT into the cancer cell nucleus ......

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