Homologous Recombination Deficiency (HRD) and BRCA 1/2 Gene Mutation for Predicting the Effect of Platinum-Based Neoadjuvant Chemotherapy of Early-Stage Triple-Negative Breast Cancer (TNBC): A Systematic Review and Meta-Analysis

Chai, Y; Chen, YJ; Zhang, D; Wei, YC; Li, ZJ; Li, Q; Xu, BH

Li, Q (通讯作者),Chinese Acad Med Sci & Peking Union Med Coll, Canc Hosp, Natl Clin Res Ctr Canc, Natl Canc Ctr,Dept Med Oncol, Beijing 100021, Peoples R China.

JOURNAL OF PERSONALIZED MEDICINE, 2022; 12 (2):

Abstract

Background: Platinum-based agents may benefit patients with triple-negative breast cancer (TNBC) whose tumors are dysfunctional in DNA repair mechanis......

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