Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system

Kim, H; Kim, JW; Kim, SJ; Choi, YJ; Kim, DS; Park, HJ

Park, HJ (reprint author), Korea Inst Toxicol, Predict Model Res Ctr, Daejeon 34114, South Korea.

STEM CELL RESEARCH, 2018; 26 (): 72

Abstract

Pregnane X receptor (PXR) is a key nuclear receptor that mediates drug metabolism and stimulates hepatocyte proliferation. However, the lack of PXR ex......

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