Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways

Chen, YJ; Wan, WH; Wu, WY; Hsu, CC; Wei, LR; Wang, SF; Hsu, YW; Liaw, CC; Tsai, WC

Tsai, WC (reprint author), Kaohsiung Med Univ, Dept Med Lab Sci & Biotechnol, Kaohsiung, Taiwan.; Tsai, WC (reprint author), Kaohsiung Med Univ, Ctr Infect Dis & Canc Res, Kaohsiung, Taiwan.; Tsai, WC (reprint author), Kaohsiung Med Univ Hosp, Dept Lab Me

PLOS ONE, 2017; 12 (8):

Abstract

Objective Pancreatic cancer is one of the most lethal types of cancer with a 5-year survival rate of similar to 5%. Histone deacetylases (HDACs) parti......

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