Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment

Wang, LJ; Guo, CL; Li, XX; Yu, XM; Li, XQ; Xu, K; Jiang, B; Jia, XL; Li, C; Shi, DY

Wang, LJ; Shi, DY (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019; 177 (): 153

Abstract

The eukaryotic initiation factor 4E (eIF4E) is an emerging anticancer drug target for specific anticancer therapy as a promising approach to overcome ......

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