Human clinical mutations in mitochondrially encoded subunits of Complex I can be successfully modeled in E. coli

Zhang, F; Dang, QCL; Vik, SB

Vik, SB (通讯作者),Southern Methodist Univ, Dept Biol Sci, Dallas, TX 75275 USA.

MITOCHONDRION, 2022; 64 (): 59

Abstract

Respiratory Complex I is the site of a large fraction of the mutations that appear to cause mitochondrial disease. Seven of its subunits are mitochond......

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