Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease

Hou, L; Xiong, XS; Park, Y; Boix, C; James, B; Sun, N; He, L; Patel, A; Zhang, ZZ; Molinie, B; Van Wittenberghe, N; Steelman, S; Nusbaum, C; Aguet, F; Ardlie, KG; Kellis, M

Kellis, M (通讯作者)，MIT, Comp Sci & Artificial Intelligence Lab, Cambridge, MA 02139 USA.;Kellis, M (通讯作者)，Broad Inst Harvard & MIT, Cambridge, MA 02142 USA.

NATURE GENETICS, 2023; ():

Abstract

Genetic variants associated with complex traits are primarily noncoding, and their effects on gene-regulatory activity remain largely uncharacterized.......

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