Predictive Value of Microdose Pharmacokinetics

van Nuland, M; Rosing, H; Huitema, ADR; Beijnen, JH

van Nuland, M (reprint author), Antoni van Leeuwenhoek Netherlands Canc Inst, Dept Pharm & Pharmacol, Louwesweg 6, NL-1066 EC Amsterdam, Netherlands.; van Nuland, M (reprint author), Netherlands Canc Inst, Div Pharmacol, Amsterdam, Netherlands.

CLINICAL PHARMACOKINETICS, 2019; 58 (10): 1221

Abstract

Phase 0 microdose trials are exploratory studies to early assess human pharmacokinetics of new chemical entities, while limiting drug exposure and ris......

Full Text Link