Chronic activation of vasopressin-2 receptors induces hypertension in Liddle mice by promoting Na 1 and water retention

Stockand, JD; Mironova, EV; Xiang, H; Soares, AG; Contreras, J; McCormick, JA; Gurley, SB; Pao, AC

Pao, AC (通讯作者),Stanford Univ, Sch Med, Dept Med, Div Nephrol, Palo Alto, CA 94305 USA.;Pao, AC (通讯作者),Vet Affairs Palo Alto Hlth Care Syst, Div Nephrol, Palo Alto, CA 94304 USA.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2022; 323 (4): F468

Abstract

The renin-angiotensin-aldosterone and arginine vasopressin-V2 receptor-aquaporin-2 (AQP2) systems converge on the epithelial Na + channel (ENaC) to re......

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