APVO210: A Bispecific Anti-CD86-IL-10 Fusion Protein (ADAPTIR (TM)) to Induce Antigen-Specific T Regulatory Type 1 Cells

Pellerin, L; Chen, P; Gregori, S; Hernandez-Hoyos, G; Bacchetta, R; Roncarolo, MG

Roncarolo, MG (reprint author), Stanford Univ, Dept Pediat, Div Stem Cell Transplantat & Regenerat Med, Stanford, CA 94305 USA.; Roncarolo, MG (reprint author), Stanford Univ, Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA.

FRONTIERS IN IMMUNOLOGY, 2018; 9 ():

Abstract

IL-10 is a potent immunosuppressive cytokine that promotes the differentiation of tolerogenic dendritic cells (DC-10), and the subsequent induction of......

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