Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins

Liu, RM; Yang, J; Yao, J; Zhao, Z; He, W; Su, N; Zhang, ZY; Zhang, CX; Zhang, Z; Cai, HB; Zhu, LY; Zhao, YZ; Quan, S; Chen, XJ; Yang, Y

Chen, XJ; Yang, Y (通讯作者)，East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Optogenet & Synthet Biol Interdisciplinary Res Ct, Shanghai, Peoples R China.;Chen, XJ; Yang, Y (通讯作者)，East China Univ Sci & Technol, Sch Pharm, Shanghai, Peoples R China.;Chen, XJ; Yang, Y (通讯作者)，Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai, Peoples R China.

NATURE BIOTECHNOLOGY, 2022; 40 (5): 779

Abstract

Photoswitchable RNA-binding proteins enable the spatiotemporal control of RNA function. RNA-binding proteins (RBPs) play an essential role in regulati......

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