Extracellular Vimentin/VWF (von Willebrand Factor) Interaction Contributes to VWF String Formation and Stroke Pathology

Fasipe, TA; Hong, SH; Da, Q; Valladolid, C; Lahey, MT; Richards, LM; Dunn, AK; Cruz, MA; Marrelli, SP

Marrelli, SP (reprint author), UTHealth, McGovern Med Sch, Dept Neurol, 6431 Fannin St,MSE R344, Houston, TX 77030 USA.; Cruz, MA (reprint author), Baylor Coll Med, Dept Med, Sect Cardiovasc Res, 2002 Holcombe,Bldg 109,R-146, Houston, TX 77030 USA.

STROKE, 2018; 49 (10): 2536

Abstract

Background and Purpose-VWF (von Willebrand factor) strings mediate spontaneous platelet adhesion in the vascular lumen, which may lead to microthrombi......

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