Rac2 regulates immune complex-mediated granule polarization and exocytosis in neutrophils

Ilarraza, R; Chao, DV; Bodman, JAR; Chesley, A; Humble, A; Shaheen, F; Eitzen, G; Lacy, P

Lacy, P (通讯作者),Univ Alberta, Dept Med, 559 HMRC,11207 87 Ave NW, Edmonton, AB T6G 2R3, Canada.

JOURNAL OF LEUKOCYTE BIOLOGY, 2023; 114 (2): 116

Abstract

A key molecule for neutrophil degranulation is Rac2 guanosine triphosphatase. Neutrophils from Rac2 knockout mice (Rac2(-/-)) exhibit impaired primary......

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