Discovery of beta-arrestin-biased beta(2)-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives

Woo, AYH; Ge, XY; Pan, L; Xing, G; Mo, YM; Xing, RJ; Li, XR; Zhang, YY; Wainer, IW; Cheng, MS; Xiao, RP

Xiao, RP (reprint author), Peking Univ, Inst Mol Med, State Key Lab Membrane Biol, Beijing 100871, Peoples R China.; Cheng, MS (reprint author), Shenyang Pharmaceut Univ, Dept Med Chem, Shenyang 110016, Peoples R China.; Cheng, MS (reprint author), Shenya

ACTA PHARMACOLOGICA SINICA, 2019; 40 (8): 1095

Abstract

beta-Arrestins are a small family of proteins important for signal transduction at G protein-coupled receptors (GPCRs). beta-Arrestins are involved in......

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