Exposure-response analyses of trastuzumab emtansine in patients with HER2-positive advanced breast cancer previously treated with trastuzumab and a taxane

Li, CZ; Wang, B; Chen, SC; Wada, R; Lu, D; Wang, X; Polhamus, D; French, J; Vadhavkar, S; Strasak, A; Smitt, M; Joshi, A; Samant, M; Quartino, A; Jin, J; Girish, S

Li, CZ (reprint author), Genentech Inc, Dept Clin Pharmacol, 1 DNA Way, San Francisco, CA 94080 USA.

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2017; 80 (6): 1079

Abstract

Purpose In the phase III EMILIA study, trastuzumab emtansine (T-DM1) significantly improved progression-free survival (PFS) and overall survival (OS) ......

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